December 2014: Recent Papers Using Luminex xMAP Technology

As 2014 comes to a close, we have one last highlight of the numerous publications from our customers. We’ve selected seven new papers, featuring customer-developed assays and partner kits, which we thought would be especially interesting to you.

Our bibliography helps you stay current with the success that your scientific peers are having while using xMAP® Technology. We’ve included hyperlinks to the PubMed citation or journal sites for your convenience.

We can’t share all of the new publications with you, as your peers publish over 300 new publications each month. A complete list of over 22,000 publications using Luminex® technology can be found at

Are there specific applications that you’d like to see us highlight?

Gene Expression

Booher R N, Hatch H, Dolinski B M, Nguyen T, Harmonay L, Al-Assaad A-S, Ayers M, Nebozhyn M, Loboda A, Hirsch H A, Zhang T, Shi B, Merkel C E, Angagaw M H, Wang Y, Long B J, Lennon X Q, Miselis N, Pucci V, Monahan J W, Lee J, Kondic A G, Im E K, Mauro D, Blanchard R, Gilliland G, Fawell S E, Zawel L, Schuller A G,Strack P. MCL1 and BCL-xL levels in solid tumors are predictive of dinaciclib-induced apoptosis. PLoS One 2014;9(10):U160-U172.

Workflow of QuantiGene® 2.0 Plex Assay from Affymetrix used in Booher et al.Workflow of QuantiGene® 2.0 Plex Assay from Affymetrix used in Booher et al.

Cytokine Profiling

Wang L, Le Mercier I, Putra J, Chen W, Liu J, Schenk A D, Nowak E C, Suriawinata A A, Li J,Noelle R J. Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity. Proceedings of the National Academy of Sciences of the United States of America 2014;111(41):14846–14851.

Shepardson K M, Jhingran A, Caffrey A, Obar J J, Suratt B T, Berwin B L, Hohl T M,Cramer R A. Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection. PLoS Pathogens 2014;10(9):U458-U473.

Transplant Diagnostics

Visentin J, Guidicelli G, Bachelet T, Jacquelinet C, Audry B, Thoa N, Dubois V, Moreau J-F, Lee J-H, Couzi L, Merville P,Taupin J-L. Denatured class I human leukocyte antigen antibodies in sensitized kidney recipients: Prevalence, relevance, and impact on organ allocation. Transplantation 2014;98(7):738–744.

Customer-Developed Drug Resistance/Mutation Testing

Gu L, Kawana-Tachikawa A, Shiino T, Nakamura H, Koga M, Kikuchi T, Adachi E, Koibuchi T, Ishida T, Gao G F, Matsushita M, Sugiura W, Iwamoto A,Hosoya N. Development and customization of a color-coded microbeads-based assay for drug resistance in HIV-1 reverse transcriptase. PLoS One 2014;9(10):U837-U848.

Customer-Developed Protein Profiling

Makiya M A, Herrick J A, Khoury P, Prussin C P, Nutman T B,Klion A D. Development of a suspension array assay in multiplex for the simultaneous measurement of serum levels of four eosinophil granule proteins. Journal of Immunological Methods 2014;411:11–22.

Immunodiagnostic Testing

Huang J, Kang B H, Pancera M, Lee J H, Tong T, Feng Y, Imamichi H, Georgiev I S, Chuang G-Y, Druz A, Doria-Rose N A, Laub L, Sliepen K, van Gils M J, de la Pena A T, Derking R, Klasse P-J, Migueles S A, Bailer R T, Alam M, Pugach P, Haynes B F, Wyatt R T, Sanders R W, Binley J M, Ward A B, Mascola J R, Kwong P D,Connors M. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature 2014;515(7525):138-142.