The VERIGENE® System utilizes advanced automation and proprietary chemistry to enable rapid, sample to result detection of nucleic acid and protein targets. NanoGrid Technology, a unique gold nanoparticle probe chemistry, is the driving force behind all VERIGENE tests, providing a versatile and extremely reliable foundation for the VERIGENE System’s growing menu of clinically meaningful diagnostics.
The gold nanoparticles utilized in NanoGrid Technology are 13-20 nanometers (nm) in diameter. One nanometer is approximately one ten-thousandth (1/10,000) of the width of a human hair.
Depending upon the application, each nanoparticle is functionalized with either a defined number of oligonucleotides (i.e., short pieces of DNA or RNA) or a defined number of antibodies that are specific to a particular protein of interest.
Gold nanoparticle probes possess several properties that make them ideal for diagnostic applications:
The detection of DNA or RNA targets on the VERIGENE System using NanoGrid Technology entails: