Guava® Nexin Reagent

Optimized for ease of use and deeper, faster scientific insights


The Guava® Nexin Reagent – 100 Tests (Part Number: 4500-0450) offers a simple, reproducible, and sensitive assessment of early apoptosis.


The Guava Nexin Reagent is a mix-and-read assay for monitoring externalization of phosphatidylserine (PS) through the binding of Annexin V to the exposed PS. Annexin V is a calcium-dependent phospholipid-binding protein with high affinity for phosphatidylserine (PS)—a membrane component normally localized to the internal side of the cell membrane. Early in the apoptotic pathway, molecules of PS are translocated to the outer surface of the cell membrane where Annexin V can readily bind to them.


The assay relies on a two-dye strategy:


  1. Annexin V-PE, which binds to PS on the external membrane of apoptotic cells
  2. 7-AAD, a fluorescent DNA intercalator that is membrane impermeant and is therefore excluded from live, healthy, and early apoptotic cells, but permeates late-stage apoptotic and dead cells


Product Information


Detection Method:




Instrument Compatibility:



For Research Use Only. Not for use in diagnostic procedures.

Guava Nexin Reagent (100 tests) – Quick Reference Card

Guava Nexin Reagent (100 tests) – User Guide

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Guava® Nexin Reagent – 100 Tests


Part Number




Ordering Information


Ordering information can be found here

  • Email your purchase order to: [email protected]
  • Phone: +1 866 401 5450
  • FAX us at: +1 512 219 0544


The following details will need to be included with your purchase orders in order to process them:

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  • Complete billing and shipping addresses
  • Product number, description, pricing, and quantity
  • Net 30 payment terms or other agreed upon payment terms
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Questions on Orders: [email protected].


Questions on Billing and Payments: [email protected].


For Research Use Only. Not for use in diagnostic procedures.