The VERIGENE™ System utilizes advanced automation and proprietary chemistry to enable rapid direct detection of nucleic acids and high-sensitivity protein detection on the same platform. The unique gold nanoparticle probe technology is the driving force behind all Verigene tests, providing a versatile and extremely reliable foundation for the Verigene System’s growing menu of clinically meaningful diagnostics.
Nanoparticles, as used in the VERIGENE System, are typically 13-20 nanometers (nm) in diameter. One nanometer is approximately one ten-thousandth (1/10,000) of the width of a human hair.
Depending upon the application, each nanoparticle is functionalized with either a defined number of oligonucleotides (i.e., short pieces of DNA or RNA) or a defined number of antibodies that are specific to a particular protein of interest.
Gold nanoparticle probes possess several properties that make them ideal for diagnostic applications:
The detection of DNA or RNA targets using nanoparticle probe technology entails:
Ultra-sensitive detection of protein targets, using nanoparticle probe technology, entails: