Partner Product Offerings: Affymetrix | R&D Systems | EMD Millipore | Luminex10月 11th, 2016 / Hilary Graham
Checkmate on Cancer – get the full view soluble immune checkpoint molecules
ProcartaPlex® Immuno-Oncology Checkpoint Molecules Panel (14 plex)
The Immuno-Oncology Checkpoint Marker Panel is the first commercially available, multiplex immunoassay system that allows the simultaneous detection of the soluble forms of the following 14 checkpoint modulators: BTLA, GITR, HVEM, IDO, LAG-3, PD-1, PD-L1, PD-L2, TIM-3, CD28, CD80, 4-1BB, CD27, and CTLA-4. These assays are also available as Simplex assays and can be added to custom Mix&Match assays to create a custom assay that allows for the simultaneous quantification of up to 80 analytes from a single small sample (25 μL for serum or plasma samples; 50 μL for cell culture supernatant).
The Immuno-Oncology Checkpoint Marker Panel is an ideal RUO solution:
- to identify responder profiles prior to treatment stratification via biomarker
- to provide complementary information to the data obtained by pathologists from tumor tissues
- to monitor disease progression in longitudinal studies
- to associate biomarker levels with checkpoint blockade therapy response
Reproduced with permission, courtesy of Affymetrix®.
Not finding what you’re looking for in a readymade panel?
Add a ProcartaPlex® Simplex Bead Set to include additional individual analytes to panels or build your own panel by combining multiple ProcartaPlex Simplex bead sets ProcartaPlex Basic Kit.
Don’t want to build your own custom assay? Affymetrix can build a custom immunoassay for you in as little as 2 weeks.
QuantiGene® Plex Assay
QuantiGene Plex assay is the highest throughput solution for multiplexed gene expression and DNA copy number variation analysis, allowing researchers to measure 3 to 80 genes in every well of a 96-well plate. Over 15,000 genes can be mixed to create custom pathway- and disease-themed panels or purchased in an off the shelf panel. Eighty-plex off the shelf RUO kits are available for the following pathways:
- Angiogenesis (human & mouse)
- Apoptosis (human & mouse)
- Breast cancer-ER (human)
- Cancer (human)
- Cell cycle (human & mouse)
- Cytokine (human & mouse)
- Drug Metabolism (human & mouse)
- Inflammation (human)
- Immunology (human & mouse)
- Jak-Stat (human & mouse)
- Kinase (human & mouse)
- p53 (human)
- Stem cell (human & mouse)
- Toxicity (human)
- Wnt signaling (human)
Learn more about the benefits and capabilities of QuantiGene Plex Assay in the resource literature.
R&D Systems, a Bio-Techne Brand
Want a custom biomarker assay? Don’t want to build it yourself?
The Luminex® Assay, by R&D Systems, offers 347 biomarkers to select from enabling you to configure the exact assay you need. This near custom assays solution is optimized to deliver the most flexible Luminex Assay available. Use the online ordering tool to see all available analytes and configurations.
Don’t see an analyte of interest on the list? Simply inquire about custom assay services.
Features of the R&D Systems Luminex Assays include:
- Available in polystyrene or magnetic bead types
- Select up to 50 biomarkers with magnetic beads or 100 in the polystyrene format
- Biomarkers available for human, mouse, and rat species
- Assays require <50 μL of sample for duplicate readings
Microspheres and biotin detection antibodies are supplied as premixed cocktails for ease of use.
MILLIPLEX® MAP Human Neuroscience Magnetic Bead Panel 1
Researching Parkinson’s Disease, Alzheimer’s Disease, or Traumatic Brain Injury?
The MILLIPLEX® MAP Human Neuroscience Magnetic Bead Panel 1 (product number HNS1MAG-95K) is a new 6-plex kit that requires only 25 μL of neat human cerebrospinal fluid (CSF) per assay. The biomarkers contained in the kit are:
- GFAP (Glial Fibrillary Acidic Protein)
- UCHL1 (Ubiquitin carboxyl-terminal hydrolase isozyme L1)
- DJ1 (Parkinson’s Disease Protein 7)
- NSE (Neuron Specific Enolase)
- TGM-2 (Transglutaminase 2)
Analytes sound familiar? While four of the analytes were contained in a previous neuroscience panel, this product has higher sensitivity due to modifications of the assay and kit components. In particular, the detectability of alpha-synuclein in CSF is much improved. HNS1MAG-95K is the only assay currently on the market that enables simultaneous detection of these 6 key neuroscience biomarkers in a single sample, allowing investigators to expand their research while conserving valuable CSF samples.
For Research Use Only. Not for use in diagnostic procedures. This assay method has not been independently evaluated by a third party certifier of government agency. Please contact [email protected] to obtain the appropriate product information for your country of residence. MultiFLEX is a trademark of GenArraytion Inc. Manufactured by GenArraytion Inc., distributed exclusively by Luminex Corporation.