Guava® TUNEL Kit

Optimized for ease of use and deeper, faster scientific insights

The Guava® TUNEL Kit – 100 Tests (Part Number: 4500-0121) detects apoptosis-induced DNA fragmentation through a quantitative fluorescence assay. Terminal deoxynucleotidyl transferase (TdT) catalyzes the incorporation of bromo-deoxyuridine (BrdU) residues into the fragmenting nuclear DNA at the 3′-hydroxyl ends by nicked-end labeling. A TRITC-conjugated anti-BrdU antibody can then label the 3′-hydroxyl ends for detection by a Guava System.

One of the hallmarks of late stage apoptosis, or programmed cell death, is the fragmentation of nuclear chromatin. As a result, the Guava TUNEL Kit can be used for detection of late-stage apoptosis.

Instrument Compatibility:

For Research Use Only. Not for use in diagnostic procedures.

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Product

Guava® TUNEL Kit – 100 Tests

Part Number

4500-0121

Ordering Information

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For Research Use Only. Not for use in diagnostic procedures.