COVID-19 Testing & Research Solutions

When it comes to coronavirus, we have flexible solutions for your testing and research needs.

In response to the global outbreak of the novel coronavirus disease (COVID-19), Luminex has developed multiple solutions to enhance our offerings in order to automate and facilitate the detection of SARS-CoV-2 and COVID-19 research.

Molecular Testing Solutions

Whether you’re looking for targeted SARS-CoV-2 detection or a comprehensive panel of respiratory pathogens that includes SARS-CoV-2—we’ve got
you covered.

Targeted

Directly test for SARS-CoV-2 in a variety of respiratory samples. These tests, all based on nucleic acid amplification, accommodate variable sample throughput—test a single sample per run, or up to 12 samples at a time.

Sample-to-Answer

Panels

These tests quickly identify multiple respiratory pathogens, including the most relevant circulating pathogen today, SARS-CoV-2. The composition of each panel is unique, enabling you to select the panel that is most suitable to your needs.

High-Throughput

These products are for Research Use Only. Not for use in diagnostic procedures. Please contact Luminex at [email protected] to obtain the appropriate product information for your country of residence.

Serology tests are part of the second phase of the testing paradigm, which is the identification of the presence of antibodies against SARS-CoV-2 in serum.

 
xMAP® SARS-CoV-2 Antibody Assay

In these uncertain times, laboratories need to have confidence in COVID-19 antibody test results—which is why Luminex has developed a comprehensive SARS-CoV-2 antibody assay. Using a combination of robust internal controls and highly-specific antigens, the xMAP® SARS-CoV-2 assay enables the rapid and reliable detection of SARS-CoV-2 antibodies in plasma or serum samples.

Learn more about our xMAP SARS-CoV-2 antibody assay.

Custom Multiplex COVID-19 Serology Assays

Serology tests, when used on human samples, are used to define the population that has been infected with the virus and developed an immunological response—as seen via the antibodies in their bloodstream against the virus. This information can be helpful for disease characterization, vaccine and drug development, as well as public health policy development. xMAP® multiplexing technology is ideally suited for the development of serological assays because it supports this key antibody detection chemistry and provides a flexible, high-throughput solution.

xMAP is a microsphere-based suspension array technology that enables the analysis of multiple targets in a single reaction, expanding the capacity to look at multiple biomarkers with reduced sample usage. Leveraging the ability to multiplex the detection of antibodies against multiple antigens of an infectious agent provides rapid and detailed information about the immune status of an individual.

Further, xMAP multiplexing technology supports both protein- (capture sandwich, indirect, competitive) and nucleic acid- (direct hybridization, OLA, ASPE, microRNA) based assay chemistries, the latter of which is used in our NxTAG® CoV Extended Panel using nasopharyngeal swab (NPS) samples.

Protein-based Assay Chemistries

As COVID-19 assay development progresses, applications of xMAP-based assays will include:

  • Immune response monitoring: tracking disease progression, mapping individual antibody expression, understanding individual and population immunity, determining previous exposure, understanding duration of protective antibodies, and selecting time points for treatments.
  • Pathogen identification and immune surveillance: tracking transmission rates, transmission methods, and co-infections.
  • Vaccine development: selecting antigen candidates, efficacy, immunogenicity, participant selection, and vaccine QC/QA testing for product release.
  • Drug development: screening candidate compounds for further investigation, PK/PD, screening patients for clinical trials, and screening convalescent plasma.
  • Public health and epidemiology: tracking global transmission, identifying zoonotic reservoirs, and transmission modeling in surrogate species.
  • Cytokine storm: cytokine profiling to inform treatment, clinical progression, and inflammation management.
  • Immunogenetics: HLA type correlation with clinical outcomes, HLA type informed treatment decisions, and donor-recipient matching.
  • Screening: Screening for high-risk personnel, military, healthcare, the travel industry, food suppliers, mail/delivery drivers, and biological donations.

Applications of Flow Cytometry in COVID-19 Research

The rapid spread of SARS-CoV-2 and the COVID-19 pandemic have underscored an urgent need to understand the mechanisms of infection, including the host immune response. COVID-19 research is being performed on the molecular, protein, and cellular levels in many different environments to devise strategies and therapeutics for mitigating the spread and impact of this strain of coronavirus.

Flow cytometry is a powerful analytical method that can be a valuable tool for many areas of COVID-19 research. Our Guava® and Amnis® systems give you instant access to all facets of cellular phenotypes and morphology, providing a comprehensive picture of the cellular immune response to COVID-19.

Luminex Flow Cytometry Systems:

Guava® Muse® Cell Analyzer

The Guava® Muse® Cell Analyzer is a powerful, compact system that uses innovative Guava microcapillary technology to provide quick and accurate absolute cell counts, viability, and basic cell health analyses.

Learn More

Guava® Muse® Cell Analyzer
The Guava® easyCyte™ System

Guava® easyCyte™ System

The Guava® easyCyte™ System is a versatile benchtop platform for multi-dimensional immunophenotyping and cell health assessment. Cellular analysis provides critical information on immune status, offering key insights into understanding immune response mechanisms

Learn More

Amnis® CellStream® Flow Cytometer

The Amnis® CellStream® Flow Cytometer is an easy-to-use, compact benchtop system that offers high-sensitivity, precise detection of viral particles. The flexible, modular design of the CellStream System allows the platform to easily grow with your evolving research needs.

Learn More

Amnis® CellStream® Flow Cytometer
Amnis® ImageStream® X Mk II Imaging Flow Cytometer

Amnis® ImageStream®X Mk II Imaging Flow Cytometer

The Amnis® ImageStream®X Mk II Imaging Flow Cytometer offers high-end detection of viral particles, which includes acquisition of image data. Along with high-powered lasers, the new High Gain mode for the ImageStream System delivers increased sensitivity for detecting small particles.

Learn More

Explore the resources below to learn how our automated, flexible, and easy-to-use flow cytometers can help accelerate discovery in your COVID-19 research.

Video Thumbnail
Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19 Research (Webinar)
When it comes to coronavirus, we have flexible solutions for your testing and research needs. In response to the global outbreak of the novel coronavirus disease (COVID-19), Luminex has developed multiple solutions to enhance our offerings in order to automate and facilitate the detection of SARS-Co

For Research Use Only. Not for use in diagnostic procedures. Please contact [email protected] to obtain the appropriate product information for your country of residence.

Related Links

To learn more about Luminex’s SARS-CoV-2 solutions outside of the EU, please check our regional websites for US, Japan, and China.


Coronavirus (COVID-19) Press Releases:

Luminex Receives FDA Emergency Use Authorization for ARIES® SARS-CoV-2 Assay to Detect Virus Responsible for COVID-19 Disease – April 6th

Luminex Receives BARDA Contract to Support Development of Second, Rapid SARS-CoV-2 Test – March 31st

Luminex Receives FDA Emergency Use Authorization for NxTAG® CoV Extended Panel to Detect the SARS-CoV-2 Virus that Causes COVID-19 Disease – March 27th

Luminex Provides Update on SARS-CoV-2 Validation Testing Efforts – March 13th

Luminex Provides Updates on Critical Efforts Related to Novel Coronavirus – March 4th


Product Information:

NxTAG® CoV Extended Panel (RUO) – Brochure

ARIES® SARS-CoV-2 Assay (RUO) – Brochure

Flow Cytometry Applications for COVID-19 Research – Flyer


Posters:

Highly Sensitive and Specific Multiplex Antibody Assays to Quantify Immunoglobulins M, A and G Against SARS-CoV-2 Antigens

Validation of FlexImmArray™ SARS-CoV-2 Human IgG Antibody Test, a High-Performance & Multiplex Serology Assay

Analysis of Viral Particles on Amnis® Flow Cytometers

Enabling COVID-19 Research with Simplified T/B Cell and PBMC Characterization

Solutions for COVID-19 Research Using Multiparametric Microcapillary Flow Cytometry


Webinars:

Development of Luminex Based Serological Test for COVID-19 Diagnosis and Monitoring

High-throughput Assay for Monitoring COVID-19 Antibodies and Their Isotypes

Rapid Development of Multiplex Serological Assays for COVID-19 and Beyonds

Applications of Flow Cytometry and Imaging Flow Cytometry to COVID-19 Research


White Papers:

Development and Evaluation of Two SARS-CoV-2 RT-PCR Laboratory Developed Tests on the ARIES® Automated, Sample-to-Answer, Real-Time PCR System

A Behind-the-Scenes Look at COVID-19 Testing at the Carl-Thiem-Klinikum (CTK) Hospital in Cottbus, Germany

Planning SARS-CoV-2 Serological Assay Development

Rush University Medical Center: Novel Serological Test for Immune Response to SARS-CoV-2 Virus

xMAP® Technology: A Benchmark for Serological Testing


Related Blogs:

METHODS Special Issue: New Assays to Characterize Vaccination and Infection History

Five Things We Learned from an xMAP Power User

Webinar: Multiplex Serological Assay Developed to Identify Avian Influenza Subtypes

METHODS Special Issue: New Multiplex Assay for Vaccine Immunogenicity Testing

METHODS Special Issue: Multiplexing Enables More Robust Surveillance for Avian Influenza

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