Precision Coupling with Molar Amounts of Protein

Precision coupling is useful for multiplex antibody assays, screening recombinant antibodies, and more! I’ve been getting a lot of requests lately to provide more information on the molar coupling method. If you’ve been wondering how it works, here’s a quick look at how to incorporate molar coupling into your assay development. When coupling whole immunoglobulins […]

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The Versatility of Multiplex Antibody Titer Assays for COVID-19 and Beyond

  The COVID-19 outbreak that began in Wuhan, China in December 2019 was marked by an increase in the number of cases showing pneumonia-like symptoms.1,2 It was not until about a month after the outbreak began that genomic analysis identified a novel coronavirus as the causative agent. With the emergence of new pathogen strains, genomic […]

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Questions to Ask When Choosing a Multiplex Assay Kit

With the COVID-19 pandemic in full swing, many researchers are looking to multiplex assays to evaluate what they call the “cytokine storm.” This refers to the increase in pro-inflammatory cytokines like IL-6 in patients with COVID-19, which is believed to predict disease severity.1 Many of Luminex’s Partners already have multiplex assays available for research use. […]

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Considerations Regarding RNA Extraction Kits for SARS-CoV-2 Detection

The novel coronavirus disease (COVID-19) pandemic continues to trigger rapid development of molecular diagnostic tests around the world. Nucleic acid amplification-based tests (NAATs)—such as real-time PCR and isothermal amplification—are the gold standard in molecular diagnostic technologies that are being utilized to detect SARS-CoV-2, the COVID-19 disease-causing virus.1 There are two critical and sequential steps that […]

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Webinar: Mouse Model Analysis Is Better with Multiplexing

Query hundreds of immunoassay targets, even with limited sample volume To make the most of immunology-focused assays using the limited tissue and fluid samples available from mouse models, scientists should consider using xMAP® Technology from Luminex, according to Daniel Braunschweig, Proteomics Field Application Scientist Leader at Bio-Rad Laboratories. That’s the takeaway from a 30-minute webinar […]

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How to Choose an Assay Development Platform

The Luminex Team knows assay development. Check out some tips from our experts below. If you need to design a new assay, there are several factors you’ll want to consider before selecting the platform you’ll develop it on. Based on our experience, these are the most important: Analyte of interest: Is your assay meant to […]

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3D Organoid Cultures Offer Clues to Heterogeneous Therapy Response in Cancer Patients

Luminex-powered DigiWest® assays show significant intratumoral differences in response A publication in PLoS Genetics sheds much-needed light on the heterogeneity of drug response within tumors. The scientists used organoid cultures with several analytical tools, including DigiWest protein expression assays, which are based on xMAP® Technology from Luminex. “Heterogeneous pathway activation and drug response modeled in […]

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MAGPIX® Systems See New Life Through Equipment Donation Program

MilliporeSigma and Seeding Labs send gently used instruments to labs in need Thanks to a nonprofit organization called Seeding Labs and our Licensed Technologies Partner MilliporeSigma, previously-owned xMAP® Technology systems are helping scientists in laboratories in developing countries around the world answer important new research questions. Seeding Labs is a Boston-based nonprofit dedicated to empowering […]

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Webinar: Fast, Economical Malaria Testing with xMAP® Technology

Multiplex assay allows for detailed investigations of transmission and drug resistance Multiplexing technology from Luminex has been critical for the development of assays designed to study human SNPs involved in parasite transmission as well as the spread of drug resistance markers in Plasmodium falciparum. That was a key message in this presentation from Lynn Grignard, […]

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Webinar: Multiplex Serological Assay Developed to Identify Avian Influenza Subtypes

Rapid detection could help prevent transmission and reduce flock losses In addition to being a public health threat, avian influenza is also costly and potentially devastating to people whose livelihoods depend on raising poultry. To enable faster detection of bird flu and identification of its subtypes, scientists at Wageningen Bioveterinary Research in The Netherlands developed a […]

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