What You Should Know About Immunogenicity Testing of Biological Drugs

Recombinant monoclonal antibodies (rMAbs) are becoming more frequently used as drugs to treat immune diseases and different types of cancer. These types of drugs are more safely degraded by the human body than traditional small molecule drugs. Small molecule drugs may cause adverse effects as they are metabolized and possibly produce toxic products. Biological drugs, […]

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The Top Five Institutions that Publish using Luminex xMAP® Technology

Luminex xMAP® Technology is used in both research and clinical diagnostics testing and has appeared in over 12,000 peer-reviewed publications. Numerous laboratories around the world use Luminex for a variety of research areas. The following institutions have published extensively with Luminex technology and a brief description of their works is included. University of Pittsburgh – […]

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Top Three Reasons that Multiplexed Biological Assays Won’t Benefit You

Most laboratories have implemented some form of multiplex assays, whether it’s in the form of a microarray, qPCR, planar array, or a suspension array. These methods have replaced many standard techniques such as Southern/Northern blots, agarose gel-electrophoresis of traditional PCR products, and enzyme-linked immunosorbent assays (ELISAs). Most labs will benefit from the acceleration of data […]

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What are Receptor Tyrosine Kinases and Why are They Important in Cancer Research?

Receptor tyrosine kinases (RTKs) are a type of cell-surface receptors and are often important in certain types of human cancer. These proteins are receptors for peptide/protein hormones including nerve growth factor (NGF), platelet derived growth factor (PDGF), fibroblast growth factor (FGF), epidermal growth factor (EGF), insulin and other cytokines/chemokines/growth factors. The active form of an […]

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Why Test for Respiratory Viruses in Your Clinical Diagnostics Lab?

In a clinical setting there are over a dozen respiratory pathogens (viral and bacterial) that are commonly encountered. A clinician needs to know which of these are infecting a patient in order to prescribe effective treatment (e.g. knowing whether an antiviral or an antibiotic is likely to be effective), and to control the spread of […]

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