TDAS Software for xTAG® GPP

Luminex’s IVD xTAG® Gastrointestinal Pathogen Panel (GPP) utilizes a new version of our TDAS software, which employs many new user-friendly features, including the ability to choose which panels or specific targets to include or mask in the final report for each sample. We will walk through the GPP data analysis process and highlight these new […]

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Four Applications Where Scientists Need to Study More than One Biomarker

Many biological systems and populations are complex interactions of multiple components. These parts of cellular pathways or ecological systems often interact in ways with each other that require scientists to study as much of the system as possible, instead of trying to look at individual components. Below are four examples where studying multiple markers or […]

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Your GPP Pre-PCR Setup Is Like a Bag of Ice for a Cocktail Party: It Has No Value Once it Reaches Room Temperature

PCR has become a rapid and reliable tool for the molecular biology-based diagnosis of a variety of infectious diseases from a wide range of clinical samples. Fecal specimens, the sample type used in our GPP assay, are among the most complex specimens for PCR. Therefore, it must be emphasized that for such a sensitive and […]

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Selecting the Right Plate Magnet for Luminex Assays

With the introduction of MagPlex® beads, more streamlined protocols can be developed for protein and nucleic acid applications. With magnetic beads, high throughput experiments being done in 96 well plates or higher formats no longer need to have washing and other buffer exchange steps done by spinning plates or washing beads with filter plates. Such […]

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Detection and Quantitation of Forty-Eight Cytokines, Chemokines, Growth Factors and Nine Acute Phase Proteins in Healthy Human Plasma, Saliva and Urine

Why do researchers want to measure multiple intercellular proteins? Well, many are potential biomarkers and by measuring multiple proteins, researchers can get a clearer picture of what is happening in biological pathways. This publication is significant because Dr. Alamgir Khan measured three different sample types, urine, saliva and plasma, to get a better understanding of […]

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Diagnosis of Gastroenteritis (aka Infectious Diarrhea): Let’s Count the Ways

Gastrointestinal infections are a significant cause of morbidity and mortality worldwide. According to the WHO World Heath Statistics report, diarrheal disease is the second leading worldwide cause of mortality in children under five years of age, accounting for 15% of all deaths in 2008. In the United States, the CDC estimates that each year, roughly […]

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Pre-treatment is Key in GPP

The pre-treatment step of your stool sample is key for optimal performance of the GPP assay. The “pre-treatment” refers to the crucial step just prior to extraction whereby we break up the stool and mechanically lyse any parasites, bacteria, or viruses present in the sample. This pre-treatment step is critical in ensuring maximum extraction efficiency, […]

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