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Category: Research Tips and Tricks

3D Organoid Cultures Offer Clues to Heterogeneous Therapy Response in Cancer Patients

Posted on by Hilary Graham
Luminex-powered DigiWest® assays show significant intratumoral differences in response A publication in PLoS Genetics sheds much-needed light on the heterogeneity of drug response within tumors. The scientists used organoid cultures with several analytical tools, including DigiWest protein expression assays, which are based on xMAP® Technology from Luminex. “Heterogeneous pathway activation and drug response modeled in […]

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MAGPIX® Systems See New Life Through Equipment Donation Program

Posted on by Hilary Graham
MilliporeSigma and Seeding Labs send gently used instruments to labs in need Thanks to a nonprofit organization called Seeding Labs and our Licensed Technologies Partner MilliporeSigma, previously-owned xMAP® Technology systems are helping scientists in laboratories in developing countries around the world answer important new research questions. Seeding Labs is a Boston-based nonprofit dedicated to empowering […]

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Webinar: Fast, Economical Malaria Testing with xMAP® Technology

Posted on by Hilary Graham
Multiplex assay allows for detailed investigations of transmission and drug resistance Multiplexing technology from Luminex has been critical for the development of assays designed to study human SNPs involved in parasite transmission as well as the spread of drug resistance markers in Plasmodium falciparum. That was a key message in this presentation from Lynn Grignard, […]

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Webinar: Multiplex Serological Assay Developed to Identify Avian Influenza Subtypes

Posted on by Hilary Graham
Rapid detection could help prevent transmission and reduce flock losses In addition to being a public health threat, avian influenza is also costly and potentially devastating to people whose livelihoods depend on raising poultry. To enable faster detection of bird flu and identification of its subtypes, scientists at Wageningen Bioveterinary Research in The Netherlands developed a […]

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Webinar: Improving Rheumatoid Arthritis Diagnostics with Multiplex Assays

Posted on by Hilary Graham
How a European team avoided performing 16,000 ELISA tests New efforts to improve the diagnosis of rheumatoid arthritis, as well as to guide treatment selection, are making strong progress thanks to xMAP® Technology from Luminex, according to a recent presentation from Erik Lönnblom of the Karolinska Institute. Multiplex immunoassays have allowed his team and collaborators […]

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METHODS Special Issue: Clinical and Analytical Performance Data for NxTAG RPP

Posted on by Hilary Graham
Highly scalable, multiplex molecular assay is comparable to xTAG RVP performance If you’ve ever used an assay based on xTAG® Technology, you may wonder how the newer NxTAG® Chemistry stacks up. A new publication in Methods uses clinical and analytical data from respiratory pathogen panels to demonstrate how both performance and workflow have improved with […]

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Custom Assays: ‘If You Dream It, We Can Multiplex It’

Posted on by Hilary Graham
Video presentation details assay development services from MilliporeSigma With new biomarkers being published every day, fewer and fewer scientists can get exactly what they need from an off-the-shelf immunoassay kit. That’s why MilliporeSigma offers extensive custom xMAP® Technology assay design and development services, which are showcased in this 10-minute video presentation from Mike Godeny, Head […]

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Webinar: Protein Conformational Analysis Goes High-Throughput with xMAP Technology

Posted on by Hilary Graham

Technique provides critical data for development of monoclonal antibodies and biosimilars At a 2018 xMAP® Connect user group meeting, Xing Wang, President of Array Bridge, spoke about how his team is using xMAP Technology to streamline the development of new biologics and biosimilars for pharma/biotech scientists. The 30-minute presentation focuses on protein conformational analysis (PCA), […]

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Now Available: Custom Assay Services from Luminex

Posted on by Hilary Graham

From full development to providing guidance, we can help you get to a functional assay—faster. The Luminex team is pleased to announce the launch of our custom development service, LuminexPLORE Lab, for assays based on xMAP® Technology. For more than 20 years, we have collaborated with customers and partners around the world in designing and […]

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METHODS Special Issue: Modifying the Luminex Workflow for Hazardous Pathogen Research

Posted on by Hilary Graham

New protocol allows scientists to create assays in containment labs and perform analysis elsewhere Scientists in the UK have developed a new protocol that utilizes Luminex multiplex assays even in specialized laboratories where space for instruments is limited. A recent hazardous pathogen study has broad implications for any research team, especially those facing space limitations. […]

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