METHODS Special Issue: Clinical and Analytical Performance Data for NxTAG RPP

Highly scalable, multiplex molecular assay is comparable to xTAG RVP performance If you’ve ever used an assay based on xTAG® Technology, you may wonder how the newer NxTAG® Chemistry stacks up. A new publication in Methods uses clinical and analytical data from respiratory pathogen panels to demonstrate how both performance and workflow have improved with […]

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METHODS Special Issue: New Multiplex Assay for Vaccine Immunogenicity Testing

Recently developed test lowers cost and reduces sample volumes needed for evaluating combination vaccines Scientists at the Serum Institute of India have developed a new multiplex immunoassay to perform the mouse immunogenicity testing recommended in many countries for quality control in the production of combination vaccines. They chose xMAP® Technology to design the serological assay, […]

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METHODS Special Issue: Multiplexing Enables More Robust Surveillance for Avian Influenza

New assay developed for routine poultry monitoring In the journal Methods, scientists from Wageningen Bioveterinary Research report the development of a multiplex assay for avian influenza. The assay is built on Luminex’s xMAP® Technology, and allows for serotyping all 16 hemagglutinin (HA) and 9 neuraminidase (NA) protein subtypes simultaneously. Testing for avian influenza (AI) is […]

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METHODS Special Issue: New Assays to Characterize Vaccination and Infection History

Single-plex targets developed will become components for future multiplex assays Scientists in the Waterboer lab at the German Cancer Institute have developed the building blocks for a multiplex assay that will make it possible to quickly interrogate a person’s history of infection and vaccination. In a paper from Methods, the team reports developing individual assays […]

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Webinar: Protein Conformational Analysis Goes High-Throughput with xMAP Technology

Technique provides critical data for development of monoclonal antibodies and biosimilars At a 2018 xMAP® Connect user group meeting, Xing Wang, President of Array Bridge, spoke about how his team is using xMAP Technology to streamline the development of new biologics and biosimilars for pharma/biotech scientists. The 30-minute presentation focuses on protein conformational analysis (PCA), […]

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METHODS Special Issue: A Universal Protocol for Attaching Any Peptide to Dyed Magnetic Beads

A new technique eliminates the use of monoclonal antibodies and is robust enough for field use Monoclonal antibodies may soon become a thing of the past. While their high selectivity and affinity for their targets once made them the “gold standard” for detection applications, the time it takes to generate one and the variability in […]

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METHODS Special Issue: Modifying the Luminex Workflow for Hazardous Pathogen Research

New protocol allows scientists to create assays in containment labs and perform analysis elsewhere Scientists in the UK have developed a new protocol that utilizes Luminex multiplex assays even in specialized laboratories where space for instruments is limited. A recent hazardous pathogen study has broad implications for any research team, especially those facing space limitations. […]

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Patient Perspective: How Precision Oncology Makes a Difference

Interview shows why clinical routine and advanced science need to work together It’s not often we get to hear the patient perspective, which makes this recent Mendelspod interview featuring a researcher and the husband of the cancer patient he’s helping particularly compelling. The 30-minute podcast features Christian Regenbrecht, CEO of Berlin-based CELLphenomics GmbH (better known […]

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Webinar: ‘The Devil Is in the Diluents’

How to manage interference in immunoassays with careful design choices Interference is a non-trivial concern when designing multiplex immunoassays, but it can be managed with careful attention to potential problems. That’s the gist of a brief video presentation from Richard Fuerstenberg, senior commercial application scientist at R&D Systems. The presentation begins with a look at […]

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Five-Minute Master Class: Design Practices for xMAP® Assays

Bio-Rad expert shares SMARTS design principles for optimizing multiplex immunoassays Ever wondered how the pros handle design for xMAP® Technology assays? This five-minute video presentation from Bio-Rad’s Amy Hendricksen offers a fast, fun look at the core design principles that are important to any multiplex immunoassay. Bio-Rad was the first Luminex partner and has been […]

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