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Customized Probe and Primer Design for SNP Detection: Development of FlexMAP™ Microsphere-Based Assays on the Luminex® Platform Using DNASIS® MAX Software
Technical Bulletin, June 2005
Excerpt: DNASIS® MAX is a sequence analysis software package produced by MiraiBio Division of Hitachi Software Engineering America Ltd. that allows users to create custom modules for algorithms and automated workflows. Here we describe the development of a workflow specifically for assays which are compatible with Luminex xMAP® technology using the FlexMAP™ microsphere assay formats.
TSH Immunoassay — third generation, extended range
Technical Bulletin, July 2002
Excerpt: Measurement of TSH (Thyroid Stimulating Hormone or Thyrotropin) is useful in screening for both hyperthyroidism, where TSH levels may be very low, and hypothyroidism, where TSH levels may be high. To date, no single commercial assay is available that exhibits both the exquisite sensitivity and broad dynamic range required for screening for both conditions. Using the xMAP system, we developed a TSH immunoassay that combines the third-generation sensitivity and the dynamic range necessary for practical use as an analytical tool.
Genotyping Dried Blood Spot DNA using the Tag-It™ CFTR 40+4 Mutation Detection Kit
This is a downloadable copy of a Technical Bulletin evaluating the compatibility of several commercially available dried blood spot DNA extraction methods with the Tag-It™ CFTR 40+4 Mutation Detection Kit.
Tm100 Universal Array
This is a downloadable copy of a Technical Bulletin explaining our Tm100 Universal Array Technology.
Signal Amplification Technology
This is a downloadable copy of a Technical Bulletin explaining our Signal Amplification Technology.
Ligand Controlled Hybridization (Specificity)
This is a downloadable copy of a Technical Bulletin explaining our Ligand Controlled Hybridization Technology. This Bulletin focuses on Ligands for use in making Hybridization reactions more specific.
Ligand Controlled Hybridization (Normalization)
This is a downloadable copy of a Technical Bulletin explaining our Ligand Controlled Hybridization Technology. This Bulletin focuses on Ligands for use in normalizing the temperatures of Hybridization reactions.
Hairpin Technical Bulletin
This is a downloadable copy of a Technical Bulletin explaining our Hairpin Capture Probe Technology.
Hairpin Squared Technical Bulletin
This is a downloadable copy of our Technical Bulletin which explains our Hairpin Squared Capture Probes
Genotyping on the Universal Array using Primer Extension Chemistry
This is a downloadable copy of a Technical Bulletin explaining the process of Genotyping using Primer Extension Chemistry on the Tm100 Universal Array.
Genotyping on the Universal Array using Ligation Chemistry
This is a downloadable copy of a Technical Bulletin explaining the process of Genotyping using Ligation Chemistry on the Tm100 Universal Array.
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