Description
Diagnosis of autoimmune diseases depends upon identifying and discriminating between multiple markers that define the proper disease classification. Luminex® xMAP® technology is well-suited to this application, as it allows for internal controls to be built into each assay. Autoimmune profiles based on xMAP technology employ microsphere sets that have been conjugated with an autoimmune antigen. A second conjugated microsphere set serves as negative control. This kind of multi-analyte profiling also provides excellent discrimination between positive and negative specimens — enabling greater specificity for fewer indeterminate results.